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Oct. 15, 2010

Stool PCR for H. pylori detection

PICO question: P: Children with chronic upper GI problems I: H pylori Stool-PCR C: Upper Endoscopy O: Diagnosis of H pylori infection Article: Application of Stool-PCR test for diagnosis of Helicobacter pylori infection in children Reviewer: Dr. J.T. Hagen

Oct. 7, 2010

Probiotics for infantile colic

Article:Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized study Reviewer: Dr. Danielle Leivian

Sept. 30, 2010

Outcomes of children exposed to chemotherapy in utero

Article: Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero. Reviewer: Dr. Delene Musielak

Sept. 24, 2010

Use of Singulair in asthma

[slideshare id=5280150&doc=ebm-sum-100924161512-phpapp01] PICO question: How does the addition of a leukotriene receptor antagonist to low-dose inhaled corticosteroids change the asthma control in children with poorly-controlled asthma, as compared to medium-dose inhaled corticosteroids? Article: Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. Bottom line: This randomized, double-blinded, adequately-powered study showed that kids with poorly-controlled…

Sept. 22, 2010

Taste test of oral rehydration solutions

Article: Assessing the palatability of oral rehydration solutions in school-aged children: a randomized crossover trial. Reviewer: Dr. Robert Mildenhall

Aug. 30, 2010

Melatonin for headache in children

[slideshare id=5279805&doc=ebm-headaches-100924152820-phpapp01] PICO question: Does Melatonin have a role in treating chronic headaches in the pediatric population? P: Pediatric population with chronic headaches (migraine or otherwise) I: Melatonin C: Continued care with routine headache therapy O: Improvement in baseline intensity, frequency or duration of headaches Article: Melatonin to prevent migraine or tension-type headache in children…

Aug. 10, 2010

Example: Nebulized hypertonic saline for bronchiolitis

PICO Question: In infants with bronchiolitis, does nebulized hypertonic saline reduce length of hospital stay compared to supportive care? Article: A randomized trial of nebulized 3% hypertonic saline with epinephrine in the treatment of acute bronchiolitis in the emergency department Bottom line: Although his randomized controlled trial adds to the evidence base, the evidence is…