Evidence based questions and answers from the Pediatrics EBM Conference at the University of Missouri.
Dupilumab for Eosinophilic Esophagitis
Article: Lancet Gastroenterol Hepatol. 2023 Nov;8(11):990-1004. Efficacy and safety of dupilumab up to 52 weeks in adults and adolescents with eosinophilic oesophagitis (LIBERTY EoE TREET study): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial Reviewer: Dr. Kelly Squires
Maternal use of antidepressants and birth defect risk
Article: JAMA Psychiatry. 2020 Dec 1;77(12):1246-1255. Maternal Use of Specific Antidepressant Medications During Early Pregnancy and the Risk of Selected Birth Defects Reviewer: Dr. Jessee Kruse
Brentuximab Vedotin for Hodgkin’s Lymphoma
Article: N Engl J Med. 2022 Nov 3;387(18):1649-1660. Brentuximab Vedotin with Chemotherapy in Pediatric High-Risk Hodgkin's Lymphoma Reviewer: Dr. Asba Memon