June 10, 2025

Dexamethasone vs. prednisone for acute asthma exacerbations

Article: J Pediatr. 2017 Dec:191:190-196.e1. "Randomized Trial of Dexamethasone Versus Prednisone for Children with Acute Asthma Exacerbations" Reviewer: Dr. Stewart Kaiser

May 27, 2025

Antibiotic therapy for febrile UTIs

Article:  Pediatrics. 2024 Jan 1;153(1):e2023062598. "Short Oral Antibiotic Therapy for Pediatric Febrile Urinary Tract Infections: A Randomized Trial" Reviewer: Dr. Tushar Ralhan 

May 20, 2025

Antibiotic therapy for community-acquired pneumonia

Article:  JAMA Pediatr. 2022 Mar 1;176(3):253-261. "Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial" Reviewer: Dr. Pete Hunter

May 13, 2025

Emollient for prevention of eczema

Article:  Lancet. 2020 Mar 21;395(10228):962-972. "Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial" Reviewer: Dr. Tyler Emery 

May 6, 2025

The role of airway clearance treatments in CF patients on modulators

Article:  Lancet Respir Med. 2023 Apr;11(4):329-340. "Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials" Reviewer: Dr. Paola Orozco

April 22, 2025

Oral lactase for colic

Article:  BMC Pediatr. 2022 Aug 3;22(1):468. "Oral lactase for infantile colic: a randomized double-blind placebo-controlled trial"  Reviewer: Dr. Makayla Goggins

April 15, 2025

Appendectomy vs. antibiotics for uncomplicated appendicitis

Article:  Lancet. 2025 Jan 18;405(10474):233-240. "Appendicectomy versus Antibiotics for Acute Uncomplicated Appendicitis in Children" Reviewer: Dr. Kamakshi Vaidyanathan 

March 18, 2025

Caffeine for apnea of prematurity

Article: New England Journal of Medicine. 2006 May 18;354(20):2112-21. "Caffeine therapy for apnea of prematurity" Reviewer: Dr. Parker Weigle 

Feb. 11, 2025

Propranolol vs Atenolol in Infants with Hemangioma

Article:  JAMA otolaryngology-- head & neck surgery. 2021 Jul 1;147(7):599-607. "Efficacy and Safety of Propranolol vs Atenolol in Infants With Problematic Infantile Hemangiomas." Reviewer: Dr. Zainab Khan

Jan. 14, 2025

Midline vs. Peripheral IV Catheters in Longer Term Pediatric Patients

Article: JAMA Pediatrics. 2023 Nov 1;177(11):1132-1140. "Midline Compared With Peripheral Intravenous Catheters for Therapy of 4 Days or Longer in Pediatric Patients. A Randomized Clinical Trial" Reviewer: Dr. Ben Legere

Jan. 7, 2025

Eat Sleep Console for Opioid Withdrawal

Article: N Engl J Med. 2023 Jun 22;388(25):2326-2337. Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal Reviewer: Dr. Stephen Troop

May 7, 2024

Shorter tuberculosis treatment in children

Article: N Engl J Med.  2022 Mar 10;386(10):911-922. "Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children." Reviewer: Dr. Brenden Stealey

April 23, 2024

Dupilumab for Eosinophilic Esophagitis

Article: Lancet Gastroenterol Hepatol. 2023 Nov;8(11):990-1004. Efficacy and safety of dupilumab up to 52 weeks in adults and adolescents with eosinophilic oesophagitis (LIBERTY EoE TREET study): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial Reviewer: Dr. Kelly Squires

April 9, 2024

Maternal use of antidepressants and birth defect risk

Article: JAMA Psychiatry. 2020 Dec 1;77(12):1246-1255. Maternal Use of Specific Antidepressant Medications During Early Pregnancy and the Risk of Selected Birth Defects Reviewer: Dr. Jessee Kruse

March 19, 2024

Brentuximab Vedotin for Hodgkin’s Lymphoma

Article: N Engl J Med. 2022 Nov 3;387(18):1649-1660. Brentuximab Vedotin with Chemotherapy in Pediatric High-Risk Hodgkin's Lymphoma Reviewer: Dr. Asba Memon

March 12, 2024

Sports physical screening for cardiac sudden death

Article: J Am Heart Assoc. 2019 Jul 16;8(14):e012235. Performance of the American Heart Association (AHA) 14-Point Evaluation Versus Electrocardiography for the Cardiovascular Screening of High School Athletes: A Prospective Study Reviewer: Dr. Chris Karow

March 5, 2024

Omalizumab for food allergies

Article: N Engl J Med. 2024 Mar 7;390(10):889-899 Omalizumab for the Treatment of Multiple Food Allergies Reviewer: Dr. Myranda Grismore  

Feb. 27, 2024

Dexamethasone vs. prednisone for acute asthma

Article: J Pediatr. 2017 Dec;191:190-196.e1. Randomized Trial of Dexamethasone Versus Prednisone for Children with Acute Asthma Exacerbations Reviewer: Dr. Bailey Clancy

Feb. 20, 2024

Antisecretory treatments for GERD

Article: Dis Esophagus. 2012 Nov-Dec;25(8):671-7. Impact of antisecretory treatment on respiratory symptoms of gastroesophageal reflux disease in children Reviewer: Dr. Emily Garrison

Feb. 13, 2024

Mother vitamin D supplementation and effect on infant bone

Article: Breastfeed Med. 2022 Jun;17(6):493-500. doi: 10.1089/bfm.2021.0281. Epub 2022 Mar 10. Comparison of Infant Bone Mineral Content and Density After Infant Daily Oral Vit D 400 IU Supplementation Versus Nursing Mother Oral 6,400 IU Supplementation: A Randomized Controlled Lactation Study Reviewer: Dr. Matthew Briese

Feb. 6, 2024

Voxelotor for sickle cell disease

Article: Lancet Haematol. 2021 May;8(5):e306-e307. PMID: 33838114 Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial. Reviewer: Dr. Ezgi Atilgan

June 20, 2023

Extended half-life rFVIIIFc for previously untreated hemophilia A

Article: Blood. 2022 Jun 30;139(26):3699-3707. First study of extended half-life rFVIIIFc in previously untreated patients with hemophilia A: PUPs A-LONG final results Reviewer: Dr. Aaron Stafford

June 13, 2023

SMART: a new strategy in asthma

Article: Chest. 2006 Dec;130(6):1733-43. Budesonide/formoterol maintenance plus reliever therapy: a new strategy in pediatric asthma Reviewer: Dr. Cece Gadaga

May 30, 2023

CBT, Sertraline or Combined Therapy for Anxiety

Article: NEJM. 2008 Dec 25;359(26):2753-66. Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety Reviewer: Dr. Julie Petro

May 23, 2023

Timolol for hemangioma

Article: JAMA Dermatol. 2021 May 1;157(5):583-587. Efficacy and Safety of Topical Timolol for the Treatment of Infantile Hemangioma in the Early Proliferative Stage: A Randomized Clinical Trial Reviewer: Dr. Sarah Shah

May 16, 2023

Rituximab for Non-Hodgkin’s Lymphoma

Article: N Engl J Med. 2020 Jun 4;382(23):2207-2219. Rituximab for High-Risk, Mature B-Cell Non-Hodgkin’s Lymphoma in Children Reviewer: Dr. Cassidy Caballero

April 18, 2023

Hydrocortisone to improve survival for extremely premature infants

Article: N Engl J Med. 2022 Mar 24;386(12):1121-1131. Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia Reviewer: Dr. Spencer Price

April 11, 2023

Early exercise for sports-related concussion

Article: Lancet Child Adolesc Health. 2021 Nov;5(11):792-799. Early targeted heart rate aerobic exercise versus placebo stretching for sport-related concussion in adolescents: a RCT Reviewer: Dr. Cedric Windom

Feb. 28, 2023

Exercise for diabetes risk reduction in children

Article: JAMA. 2012 Sep 19;308(11):1103-12. Exercise dose and diabetes risk in overweight and obese children: A RCT Reviewer: Dr. Anna Davis

Feb. 21, 2023

Motivational interviewing for obesity

Article: Pediatrics. 2015 Apr;135(4):649-57 Motivational interviewing and dietary counseling for obesity in primary care: an RCT Reviewer: Dr. Manal Salim

Jan. 24, 2023

Infliximab first-line treatment for Crohn’s disease in children

Article: Gut. 2022 Jan;71(1):34-42. First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn's disease: an open-label multicentre randomised controlled trial Reviewer: Dr. Erik Clutter

Jan. 10, 2023

Estrogen for Hypogonadism

Article: Int J Pediatr Endocrinol. 2014;2014(1):12. A Randomized Trial of Transdermal and Oral Estrogen Therapy in Adolescent Girls with Hypogonadism Reviewer: Dr. Michelle Maskeri

June 14, 2022

Noninvasive ventilation in preterm infants

Article: N Engl J Med. 2013 Aug 15;369(7):611-20. doi: 10.1056/NEJMoa1214533. A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants Reviewer: Dr. Abiola Akande

June 7, 2022

Virtual reality for cerebral palsy

Article: Phys Ther. 2018 Jan 1;98(1):63-77. doi: 10.1093/ptj/pzx107. Effectiveness of Virtual Reality in Children with Cerebral Palsy: A Systematic Review and Meta-Analysis Reviewer: Dr. Ashley Schaeffer

May 31, 2022

Balloon dilation of the eustachian tube in children

Article: Int J Pediatr Otorhinolaryngol. 2022 Mar;154:111048. doi: 10.1016/j.ijporl.2022.111048. Epub 2022 Jan 21. Efficacy and safety of balloon dilation of eustachian tube in children: Systematic review and meta-analysis Reviewer: Dr. Bilel Amor

May 24, 2022

Non-surgical vs. surgical management of appendicitis

Article: JAMA. 2020 Aug 11;324(6):581-593. doi: 10.1001/jama.2020.10888. Association of Nonoperative Management Using Antibiotic Therapy vs Laparoscopic Appendectomy with Treatment Success and Disability Days in Children with Uncomplicated Appendicitis Reviewer: Dr. Landon Olson

May 17, 2022

Immunotherapy for rhinitis

Article: Am J Rhinol Allergy. Mar-Apr 2014;28(2):131-9. doi: 10.2500/ajra.2014.28.4006. Efficacy and safety of sublingual immunotherapy in children aged 3-13 years with allergic rhinitis Reviewer: Dr. Janki Patel

March 29, 2022

Peanut Consumption in Infants

Article: N Engl J Med. 2015 Feb 26;372(9):803-13. doi: 10.1056/NEJMoa1414850. Epub 2015 Feb 23. Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy Reviewer: Dr. Jessica Doran

March 15, 2022

Bariatric Surgery in Adolescents vs. Adults

Article: N Engl J Med. 2019 May 30;380(22):2136-2145. doi: 10.1056/NEJMoa1813909. Epub 2019 May 16 Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults Reviewer: Dr. Josh Hall

March 8, 2022

Probiotics for functional abdominal pain in children

Article: Clin Nutr. 2020 Dec;39(12):3645-3651. doi: 10.1016/j.clnu.2020.04.019. Epub 2020 Apr 21. Lactobacillus reuteri DSM 17938 is effective in the treatment of functional abdominal pain in children: Results of the double-blind randomized study Reviewer: Dr. Steven Liu

Feb. 22, 2022

Cultural differences in motor development screening

Article: Dev Med Child Neurol. 2016 Dec;58(12):1213-1222. doi: 10.1111/dmcn.13263. Epub 2016 Oct 4. Cross-cultural validity of standardized motor development screening and assessment tools: a systematic review Reviewer: Dr. Catherine Du

Jan. 25, 2022

Whole-Body Hypothermia for Neonates with HIE

Article: N Engl J Med. 2005 Oct 13;353(15):1574-84. doi: 10.1056/NEJMcps050929. Whole-Body Hypothermia for Neonates with Hypoxic-Ischemic Encephalopathy Reviewer: Dr. Preston Wheeler

Jan. 11, 2022

Weight Loss Interventions for Adolescents with Intellectual Disabilities

Article: Pediatrics. 2021 Sep;148(3):e2021050261. Weight Loss Interventions for Adolescents With Intellectual Disabilities: An RCT Reviewer: Dr. Dalia Ishaq

June 1, 2021

Antibiotics associated with C. diff infections in children

Article: Pediatr Infect Dis J. 2021 May 1;40(5):426-428. doi: 10.1097/INF.0000000000002991. Impact of Antecedent Antibiotic Usage on Community-associated Clostridioides difficile Infection in Pediatrics Reviewer: Dr. Pulcherie Guissou

May 25, 2021

CBT for ADHD

Article: J Child Psychol Psychiatry. 2016 Nov;57(11):1218-1226. doi: 10.1111/jcpp.12549. Epub 2016 Mar 17. A randomized controlled trial of cognitive behavioral therapy for ADHD in medication-treated adolescents Reviewer: Dr. Elly Ranum

April 27, 2021

Paracetamol vs Ibuprofen in PDA

Article: J Pediatr. 2020 Jul;222:79-84.e2. doi: 10.1016/j.jpeds.2020.01.058. Epub 2020 Apr 24. Oral Paracetamol vs Oral Ibuprofen in Patent Ductus Arteriosus: A Randomized, Controlled, Noninferiority Trial Reviewer: Dr. Jacqueline Santamarina

March 23, 2021

IVIG for MIS-C

Article: JAMA. 2021 Mar 2;325(9):855-864. doi: 10.1001/jama.2021.0694. Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children Reviewer: Dr. John Rockett

Feb. 16, 2021

Prokinetic Agents in Neonates with Gastroschisis

Article: J Pediatr Surg. 2004 Apr;39(4):565-9. doi: 10.1016/j.jpedsurg.2003.12.020. A multicenter, randomized, double-blind, placebo-controlled trial of the prokinetic agent erythromycin in the postoperative recovery of infants with gastroschisis Reviewer: Dr. Rachel Couch

Jan. 26, 2021

Vertical transmission of coronavirus

Article: Am J Obstet Gynecol. 2021 Jan;224(1):35-53.e3. Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis Reviewer: Dr. Parker Russell

Nov. 17, 2020

Erythropoietin for Neuroprotection in Preterm Infants

Article: N Engl J Med. 2020 Jan 16;382(3):233-243. A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants Reviewer: Dr. Shruti Sinha

Sept. 22, 2020

Nirsevimab for Prevention of RSV

Article: N Engl J Med. 2020 Jul 30;383(5):415-425. Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants Reviewer: Dr. Shreeya Chugh

Aug. 25, 2020

Etanercept with IVIG for Acute Kawasaki Disease

Article: Pediatrics. 2019 Jun;143(6):e20183675 Etanercept With IVIg for Acute Kawasaki Disease: A Randomized Controlled Trial Reviewer: Dr. Varun Manohara

May 24, 2020

Caffeine therapy for apnea of prematurity

Article: New England Journal of Medicine. 2006 May 18;354(20):2112-21. Caffeine Therapy for Apnea of Prematurity Reviewer: Dr. Spencer Lambdin

April 28, 2020

Anti-inflammatories for obstructive sleep apnea in children

Article: Cochrane Database Systematic Reviews 2020 Jan 17;1:CD007074. Anti-inflammatory Medications for Obstructive Sleep Apnea in Children Reviewer: Dr.Secil Aydinoz

March 24, 2020

Immunotherapy for peanut allergy

Article: Lancet. 2019 Oct 19;394(10207):1437-1449. Sustained Outcomes in Oral Immunotherapy for Peanut Allergy (POISED Study): A Large, Randomised, Double-Blind, Placebo-Controlled, Phase 2 Study Reviewer: Dr. Brandon Kozinski

Jan. 28, 2020

Probiotics for IBS

Article: J Clin Gastroenterol , 52 Suppl 1, 2018 Effectiveness of Probiotics in Children With Functional Abdominal Pain Disorders and Functional Constipation: A Systematic Review Reviewer: Dr. Jennae Reken

Sept. 24, 2019

Management of Neonatal Abstinence Syndrome

Article:Hosp Pediatr, 9 (8), 615-623 Aug 2019 Reduction in Length of Stay and Morphine Use for NAS With the "Eat, Sleep, Console" Method Reviewer:Dr. Brieanna Kroeger

Aug. 25, 2019

Use of Continuous Inhaled Antibiotics in Cystic Fibrosis

Article: Inhaled Anti-Pseudomonal Antibiotics for Long-Term Therapy in Cystic Fibrosis Reviewer: Dr. Sarah Christenberry

July 20, 2019

Levetiracetam vs. phenytoin for status epilepticus

Article: Lancet. 2019 May 25; 393(10186): 2125–2134. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial Reviewer: Dr. Jessica Johnson

May 28, 2019

Adolescent self-consent for vaccination

Article: Vaccine. 2019 Jan 14;37(3):417-429. Barriers and enablers to adolescent self-consent for vaccination: A mixed-methods evidence synthesis Reviewer: Dr. Nathan Beckett

April 18, 2019

Probiotics for gastroenteritis

Article: N Engl J Med. 2018 Nov 22;379(21):2002-2014. Lactobacillus rhamnosus GG versus Placebo for Acute Gastroenteritis in Children Reviewer: Dr. Camilo Pineda

March 26, 2019

Oseltamivir safety and effectiveness

Article: Clin Infect Dis. 2018 May 2;66(10):1492-1500. Efficacy and Safety of Oseltamivir in Children: Systematic Review and Individual Patient Data Meta-analysis of Randomized Controlled Trials Reviewer: Dr. Paulina Perez

Feb. 26, 2019

Oral dextrose gel to treat hypoglycemia

Article: Cochrane Database Syst Rev. 2016 May 4;(5):CD011027 Oral dextrose gel for the treatment of hypoglycaemia in newborn infants Reviewer: Dr. Emma Wright

Jan. 22, 2019

Antibiotics for MRSA

Article: N Engl J Med. 2017 Jun 29;376(26):2545-2555. A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses. Reviewer: Dr. Carmen Mostek

Sept. 25, 2018

ACTH for infantile spasms

Article: Lancet Neurol. 2017 Jan;16(1):33-42. doi: 10.1016/S1474-4422(16)30294-0. Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS): a randomised, multicentre, open-label trial Reviewer: Dr. Taylor Goldhammer

Aug. 28, 2018

Cyproheptadine as appetite stimulant in children

Article: Iran J Pediatr. 2014 Dec;24(6):753-8. Epub 2014 Dec 12. Beneficial effect of cyproheptadine on body mass index in undernourished children: a randomized controlled trial Reviewer: Dr. Nwamaka Akabogu

May 31, 2018

Reducing antibiotic use for well-appearing infants of mothers with chorioamnionitis

Article: Pediatrics. 2018 Apr;141(4). Clinical Monitoring of Well-Appearing Infants Born to Mothers With Chorioamnionitis Reviewer: Dr. Heather Vannoy

May 24, 2018

Home phototherapy as a prevention of readmission

Article: J Trop Pediatr. 2015 Apr;61(2):113-8. Low-cost home-use light-emitting-diode phototherapy as an alternative to conventional methods. Reviewer: Dr. Kara Mohr

May 3, 2018

Acid-suppressants and antibiotics during infancy and associated allergies

Article: JAMA Pediatr. 2018 Apr 2:e180315 Association Between Use of Acid-Suppressive Medications and Antibiotics During Infancy and Allergic Diseases in Early Childhood Reviewer: Dr. David Gubernick

April 26, 2018

Feeding during therapeutic hypothermia in neonatal HIE

Article: Neonatology. 2018 Mar 6;113(4):347-352. Enteral Feeding as an Adjunct to Hypothermia in Neonates with Hypoxic-Ischemic Encephalopathy Reviewer: Dr. Karman Low

April 19, 2018

IVIG for Toxic Shock Syndrome

Article: Clin Infect Dis. 2014 Sep 15;59(6):851-7. Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study Reviewer: Dr. Laura Gibbons

March 29, 2018

Oscillococcinum for influenza

Article: Cochrane Database Syst Rev. 2015 Jan 28;1:CD001957. Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness Reviewer: Dr. Beth Crawford

March 22, 2018

Benzodiazepenes and prolonged ICU stay in children

Article: Crit Care Med. 2017 Sep;45(9):1427-1435. Delirium and Benzodiazepines Associated With Prolonged ICU Stay in Critically Ill Infants and Young Children. Reviewer: Dr. Daniela Navarrete

March 15, 2018

Non-invasive ventilation outcomes in intensive care

Article: Crit Care Med. 2017 Jun;45(6):1045-1053 Outcomes for Children Receiving Noninvasive Ventilation as the First-Line Mode of Mechanical Ventilation at Intensive Care Admission: A Propensity Score-Matched Cohort Study Reviewer: Dr. Christopher Miller

Feb. 15, 2018

Oseltamivir Effectiveness in Children

Article: Clin Infect Dis. 2017 Nov 23. Efficacy and Safety of Oseltamivir in Children: Systematic Review and Individual Patient Data Meta-analysis of Randomized Controlled Trials Reviewer: Dr. Jessica Luebbering

Feb. 1, 2018

Does inhaled corticosteroid use correlate with bone fracture?

Article: JAMA Pediatr. 2018 Jan 1;172(1):57-64. Association Between Inhaled Corticosteroid Use and Bone Fracture in Children With Asthma Reviewer: Dr. Sajal Patel

Jan. 25, 2018

Lactobacillus to treat infantile colic

Article:Pediatrics. 2018 Jan;141(1). pii: e20171811. Lactobacillus reuteri to Treat Infant Colic: A Meta-analysis. Reviewer: Dr. Isha Dave

Dec. 7, 2017

Texting Teens and Their Caregivers about Diabetes

Article: J Diabetes Sci Technol. 2017 May;11(3):468-475. NICH at Its Best for Diabetes at Its Worst: Texting Teens and Their Caregivers for Better Outcomes Reviewer: Dr. Sirish Rao

Sept. 28, 2017

IV vs Oral Antibiotics for Postdischarge Treatment of Acute Osteomyelitis

Article: JAMA Pediatr. 2015 Feb;169(2):120-8. Comparative effectiveness of intravenous vs oral antibiotics for postdischarge treatment of acute osteomyelitis in children Reviewer: Dr. Jonathan Hartley

Sept. 21, 2017

Skin-to-Skin Contact for Mothers and Newborn Infants

Article: Cochrane Database Syst Rev. 2016 Nov 25;11:CD003519. Early skin-to-skin contact for mothers and their healthy newborn infants Reviewer: Dr. Jonathan Shirshekan

Sept. 7, 2017

Vancomycin in the Treatment of GBS+ Mothers

Article: J Matern Fetal Neonatal Med. 2018 Apr;31(8):1021-1024. Transplacental passage of vancomycin. Reviewer:Dr. Craig Becker

Aug. 31, 2017

Early physical activity and concussion

Article:JAMA. 2016 Dec 20;316(23):2504-2514 Association Between Early Participation in Physical Activity Following Acute Concussion and Persistent Postconcussive Symptoms in Children and Adolescents Reviewer: Dr. Kimber Barrett

Aug. 24, 2017

Oxandrolone cardiometabolic effects in Klinefelter Syndrome

Article: J Clin Endocrinol Metab. 2017 Jan 1;102(1):176-184. Effects of Oxandrolone on Cardiometabolic Health in Boys With Klinefelter Syndrome: A Randomized Controlled Trial Reviewer: Dr. Stephanie Tosh

Aug. 3, 2017

Outcomes in very premature boys vs. girls

Article: Pediatr Res. 2012 Mar;71(3):305-10. Neonatal and infant outcome in boys and girls born very prematurely Reviewer: Dr. Michelle Kenney

July 27, 2017

Pictograms to reduce liquid medication dosing errors

Article: Arch Pediatr Adolesc Med. 2008 Sep;162(9):814-22. Randomized Controlled Trial of a Pictogram-Based Intervention to Reduce Liquid Medication Dosing Errors and Improve Adherence Among Caregivers of Young Children Reviewer: Dr. Jamie Ball

June 29, 2017

Risk of Serious Bacterial Infections in Febrile Infants

Article: Pediatrics. 140(1):e20170695, June 2017. The Yale Observation Scale Score and the Risk of Serious Bacterial Infections in Febrile Infants Reviewer: Dr. Isha Dave

June 22, 2017

IVIG for Guillain-Barre

Article: Pediatrics. 2005 Jul;116(1):8-14. Intravenously Administered Immunoglobulin in the Treatment of Childhood Guillain-Barre´ Syndrome: A Randomized Trial Reviewer: Dr. Jamie Ball

June 15, 2017

Timing of Food Introduction & Development of Food Sensitization

Article: Pediatr Allergy Immunol. 2017 May 29 Timing of food introduction and development of food sensitization in a prospective birth cohort. Reviewer: Dr. Kailey Wilson

June 8, 2017

Melatonin dosing in childhood insomnia

Article: Psychopharmacology (Berl). 2010 Oct;212(3):379-91 Dose finding of melatonin for chronic idiopathic childhood sleep onset insomnia: an RCT. Reviewer: Dr. Heather Vannoy

June 1, 2017

Bedside Ultrasonographic Skin Marking in Infant Lumbar Puncture

Article: Ann Emerg Med. 2017 May;69(5):610-619.e1. The Effect of Bedside Ultrasonographic Skin Marking on Infant Lumbar Puncture Success: A Randomized Controlled Trial. Reviewer: Dr. Sirish Rao

May 25, 2017

Are inhaled corticosteroids associated with HPA axis suppression?

Article: Paediatr Child Health. 2012 May;17(5):e34-9. Prevalence of hypothalamic-pituitary-adrenal axis suppression in children treated for asthma with inhaled corticosteroid. Reviewer: Dr. Laura Gibbons

May 18, 2017

Endometriosis/dysmenorrhea and diet

Article: Eur J Obstet Gynecol Reprod Biol. 2013 Jul;169(2):162-71. Endometriosis, dysmenorrhoea and diet Reviewer: Dr. Kara Mohr

April 27, 2017

Early versus Late Parenteral Nutrition in Critically Ill Children

Article: N Engl J Med. 2016 Mar 24;374(12):1111-22. Early versus Late Parenteral Nutrition in Critically Ill Children Reviewer: Dr. Christopher Miller

April 20, 2017

Lidocaine for local anesthesia duing lumbar puncture

Article: Pediatr Emerg Care. 2012 Jul;28(7):687-90. Needle-free jet injection of lidocaine for local anesthesia during lumbar puncture: a randomized controlled trial. Reviewer: Dr. Christian Gonzalez

April 6, 2017

Can improved sleep reduce ADHD symptoms?

Article: J Pediatr Health Care. 2016 Nov - Dec;30(6):e43-e48 An Intervention to Promote Sleep and Reduce ADHD Symptoms Reviewer: Dr. Gordon Duval

March 30, 2017

Social and mobile tools for weight loss

Article: Lancet Diabetes Endocrinol. 2016 Sep;4(9):747-55. Using social and mobile tools for weight loss in overweight and obese young adults (Project SMART): a 2 year, parallel-group, randomised, controlled trial. Reviewer: Dr. Jason Blake

March 23, 2017

Electronic directly observed therapy to improve hydroxyurea adherence

Article: Pediatr Blood Cancer. 2014 Jun;61(6):1068-73. A pilot study of electronic directly observed therapy to improve hydroxyurea adherence in pediatric patients with sickle-cell disease Reviewer: Dr. Rula Khreis

March 9, 2017

Maternal vs. Infant Supplementation During Lactation

Article: Pediatrics. 2015 Oct;136(4):625-34. Maternal Versus Infant Vitamin D Supplementation During Lactation: A Randomized Controlled Trial. Reviewer: Dr. Kailey Wilson

March 2, 2017

Steroid Use in the Treatment of Acute Rheumatic Carditis

Article: Pediatrics. 1961 May;27:692-706. The treatment of acute rheumatic fever. Reviewer: Dr. Biribwa Arinaitwe

Feb. 23, 2017

Stimulant Use and Bone Mass in Children

Article: JAMA Pediatr. 2016 Dec 5;170(12):e162804. Association of Stimulant Medication Use With Bone Mass in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder Reviewer:Dr. Sajal Patel

Feb. 16, 2017

Cardiac Adverse Effects of Levalbuterol and Albuterol

Article: J Pediatr Pharmacol Ther. 2011 Jul;16(3):191-8. Comparison of levalbuterol and racemic albuterol based on cardiac adverse effects in children Reviewer: Dr. Sevilay Dalabih

Feb. 2, 2017

Does Increased Duration of Paid Maternity Leave Lower Infant Mortality?

Article: PLoS Med. 2016 Mar 29;13(3):e1001985. Increased Duration of Paid Maternity Leave Lowers Infant Mortality in Low- and Middle-Income Countries: A Quasi-Experimental Study Reviewer: Dr. Chad McCormick

Jan. 26, 2017

Dexamethasone vs Prednisolone in Acute Asthma Exacerbations

Article: J Pediatr. 2015 Sep;167(3):639-44.e1. Comparative Effectiveness of Dexamethasone versus Prednisone in Children Hospitalized with Asthma Reviewer: Dr. Kara Mohr

Jan. 19, 2017

Do Antibiotic Locks Help to Prevent Neonatal CLABSI?

Article:Cochrane Database Syst Rev. 2015 Jun 4;(6):CD010336. Antibiotic lock for the prevention of catheter-related infection in neonates Reviewer: Dr. Ryan Virden

Jan. 12, 2017

Nebulized Hypertonic Saline for Infants with Viral Bronchiolitis

Article:JAMA Pediatr. 2014 Jul;168(7):657-63. Nebulized hypertonic saline for bronchiolitis: a randomized clinical trial. Reviewer: Dr. David Gubernick

Dec. 15, 2016

Can probiotics prevent antibiotic associated diarrhea?

Article: Cochrane Database Syst Rev. 2015 Dec 22;(12):CD004827. doi: 10.1002/14651858.CD004827.pub4. Probiotics for the prevention of pediatric antibiotic-associated diarrhea Reviewer: Dr. Sirish Rao

Nov. 17, 2016

Is ondansetron (zofran) associated with ventricular arrythmias?

Article:J Pediatr. 2016 Dec;179:118-123.e1. doi: 10.1016/j.jpeds.2016.08.058. Epub 2016 Sep 21. Risk of Ventricular Arrhythmias and Association with Ondansetron Reviewer:Dr. Adam Massey

Nov. 3, 2016

Does delivery mode affect composition of neonatal gut microbiota ?

Article:J Allergy Clin Immunol. 2016 Sep;138(3):881-889.e2. doi: 10.1016/j.jaci.2016.01.028. Epub 2016 Apr 1. Cesarean section changes neonatal gut colonization Reviewer:Dr. Lila Wahidi

Oct. 20, 2016

Screening for mold infections in pediatric oncology patients

Article: Support Care Cancer. 2016 Dec;24(12):5025-5033. Epub 2016 Aug 12. Application of a standardized screening protocol for diagnosis of invasive mold infections in children with hematologic malignancies. Reviewer: Dr. Jen Kovatch

Oct. 13, 2016

Management of infants with fever

Article: Pediatrics. 2016 Aug;138(2). pii: e20154381. doi: 10.1542/peds.2015-4381. Epub 2016 Jul 5. Validation of the "Step-by-Step" Approach in the Management of Young Febrile Infants. Reviewer: Dr. Jonathan Shirshekan

Sept. 29, 2016

Do glasses make vision worse over time versus not having glasses?

Article: Vision Res. 2002 Oct;42(22):2555-9. Undercorrection of myopia enhances rather than inhibits myopia progression. Reviewer: Dr. Christopher Cates

Sept. 22, 2016

I.V. vs. rectal acetaminophen after surgery

Article: Br J Anaesth. 2008 Feb;100(2):251-5. doi: 10.1093/bja/aem377. Randomized controlled trial of duration of analgesia following intravenous or rectal acetaminophen after adenotonsillectomy in children

Sept. 15, 2016

Is phototherapy associated with cancer?

Article:Pediatrics. 2016 Jun;137(6). pii: e20151353. doi: 10.1542/peds.2015-1353. Neonatal Phototherapy and Infantile Cancer Reviewer: Dr. Kaleen Long

Sept. 1, 2016

Laundry pod injuries

Article: Inj Prev. 2016 Jun 23. doi: 10.1136/injuryprev-2016-041997. Laundry pod and non-pod detergent related emergency department visits occurring in children in the USA Reviewer: Dr. Katie Blount

Aug. 25, 2016

Developmental outcomes of neonatal hypoglycemia

Article: N Engl J Med. 2015 Oct 15;373(16):1507-18. doi: 10.1056/NEJMoa1504909. Neonatal Glycemia and Neurodevelopmental Outcomes at 2 Years Reviewer:Dr. Craig Becker

June 30, 2016

Azithromycin versus Doxycycline for Chlamydia

Article: N Engl J Med. 2015 Dec 24;373(26):2512-21. doi: 10.1056/NEJMoa1502599. Azithromycin versus Doxycycline for Urogenital Chlamydia trachomatis infection Reviewer: Dr. Adam Massey

June 16, 2016

Montelukast for moderate to severe allergic rhinitis

Article: J Laryngol Otol. 2014 Mar;128(3):242-8. doi: 10.1017/S002221511400036X. Epub 2014 Mar 11 Quality of life assessment in patients with moderate to severe allergic rhinitis treated with montelukast and/or intranasal steroids: a randomised, double-blind, placebo-controlled study Reviewer: Dr. Sevilay Dalabih

June 9, 2016

Probiotics for NEC in preterm infants

Article: J Pediatr Surg. 2015 Aug;50(8):1405-12. doi: 10.1016/j.jpedsurg.2015.05.008. Epub 2015 May 27. Probiotic administration can prevent necrotizing enterocolitis in preterm infants: A meta-analysis Reviewer: Dr. Bethany Crawford

June 2, 2016

BMI in adolescence and adult health outcomes

Article: N Engl J Med. 2016 Apr 13. Body-Mass Index in 2.3 Million Adolescents and Cardiovascular Death in Adulthood Reviewer: Dr. Chris Miller

May 26, 2016

Does early introduction of allergenic foods decrease the risk of food allergy?

Article: N Engl J Med. 2016 May 5;374(18):1733-43. doi: 10.1056/NEJMoa1514210. Epub 2016 Mar 4. Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants Reviewer: Dr. Lisa Hiskey

May 19, 2016

Does fever help children fight infections?

Article: J Pediatr. 2013 Sep;163(3):822-7.e1-2. doi: 10.1016/j.jpeds.2013.03.069. Epub 2013 May 8. Does the Use of Antipyretics in Children Who Have Acute Infections Prolong Febrile Illness? A Systematic Review and Meta-Analysis Reviewer: Dr. Alex James

May 12, 2016

Otitis media treatment: watchful waiting or antibiotics

Article: Cochrane Database Syst Rev. 2016 Jun 12;6:CD009163 Antibiotics for otitis media with effusion in children. Reviewer: Dr. Rula Khreis

May 5, 2016

Iron therapy to decrease blood lead in infants

Article: J Trace Elem Med Biol. 2014 Jan;28(1):56-9. doi: 10.1016/j.jtemb.2013.11.003. Epub 2013 Nov 23. Effects of iron therapy on blood lead concentrations in infants Reviewer: Dr. Katie Blount

April 21, 2016

Videolaryngoscopy for Neonatal Intubation Education

Article:Pediatrics. 2015 Nov;136(5):912-9. doi: 10.1542/peds.2015-1028. Epub 2015 Oct 19. Videolaryngoscopy to Teach Neonatal Intubation: A Randomized Trial Reviewer: Dr. Sirish Rao

April 7, 2016

Resident Duty Hours- Effects on Patient Outcomes and Resident Well-Being

Article: N Engl J Med. 2016 Feb 25;374(8):713-27. doi: 10.1056/NEJMoa1515724. Epub 2016 Feb 2. National Cluster-Randomized Trial of Duty-Hour Flexibility in Surgical Training Reviewer: Dr. Dana Vietti

March 31, 2016

End of Life Quality of Care for Children with Cancer

Article Title: J Clin Oncol. 2005 Dec 20;23(36):9155-61. Epub 2005 Sep 19. Parent and Physician Perspectives on Quality of Care at the End of Life in Children With Cancer Reviewer: Dr. Jen Kovatch

March 24, 2016

Prefilled medication syringes in pediatric code situations

Article Ann Emerg Med. 2015 Aug;66(2):97-106.e3. doi: 10.1016/j.annemergmed.2014.12.035. Epub 2015 Feb 18. Color-Coded Prefilled Medication Syringes Decrease Time to Delivery and Dosing Error in Simulated Emergency Department Pediatric Resuscitations. Reviewer: Dr. Chad McCormick

March 17, 2016

Asynchronous Learning for Residents and Medical Students

Article: Acad Emerg Med. 2009 Dec;16 Suppl 2:S46-50. doi: 10.1111/j.1553-2712.2009.00598.x. Evaluation of a web-based asynchronous pediatric emergency medicine learning tool for residents and medical students. Reviewer: Dr. Natalie Behrle

March 10, 2016

Urokinase Versus VATS for Treatment of Empyema

Article: Pediatrics. 2014 Nov;134(5):e1301-7. doi: 10.1542/peds.2013-3935. Urokinase versus VATS for treatment of empyema: a randomized multicenter clinical trial. Reviewer: Dr. Lance Robbins

Feb. 25, 2016

Breastfeeding and health outcomes

Article: Lancet. 2016 Jan 30;387(10017):475-90. doi: 10.1016/S0140-6736(15)01024-7. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. Reviewer: Dr. Gordon Duval

Feb. 11, 2016

Early Enteral Nutrition in Acute Pancreatitis

Article: J Pediatr. 2015 Aug;167(2):397-402.e1. doi: 10.1016/j.jpeds.2015.05.030. Early Enteral Nutrition and Aggressive Fluid Resuscitation are Associated with Improved Clinical Outcomes in Acute Pancreatitis Reviewer: Dr. Kara Mohr

Jan. 28, 2016

Treatment of sleep disorders in patients with ADHD

Article: J Child Adolesc Psychopharmacol. 2013 Dec;23(10):640-7. doi: 10.1089/cap.2013.0059. Epub 2013 Nov 21. To sleep or not to sleep: a systematic review of the literature of pharmacological treatments of insomnia in children and adolescents with attention-deficit/hyperactivity disorder. Reviewer: Dr. Kaleen Long

Jan. 21, 2016

Omega three fatty acid supplementation and its effects on ADHD Patients

Article: Prostaglandins Leukot Essent Fatty Acids. 2014 Jul-Aug;91(1-2):49-60. doi: 10.1016/j.plefa.2014.04.004. Epub 2014 May 28. Effect of supplementation with long-chain ω-3 polyunsaturated fatty acids on behavior and cognition in children with attention deficit/hyperactivity disorder (ADHD): a randomized placebo-controlled intervention trial. Reviewer: Dr. Kailey Wilson

Jan. 14, 2016

Riboflavin prophylaxis for migraine

Article: J Headache Pain. 2009 Oct;10(5):361-5. doi: 10.1007/s10194-009-0142-2. Epub 2009 Aug 1. Riboflavin prophylaxis in pediatric and adolescent migraine Reviewer: Dr. Christain Gonzalez

Dec. 10, 2015

Delayed cord clamping benefits

Article: Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes (Review) Reviewer: Dr. Rebecca Fish

Nov. 12, 2015

GERD therapy for management of OME

Article: Arch Otolaryngol Head Neck Surg. 2011 Jan;137(1):35-41. doi: 10.1001/archoto.2010.222. A prospective study of the effect of gastroesophageal reflux disease treatment on children with otitis media. Reviewer: Dr. Faeza Khan

Nov. 5, 2015

Pseudomonas clearance in cystic fibrosis patients

Article: Pediatr Pulmonol. 2012 Nov;47(11):1113-22. doi: 10.1002/ppul.22543. Epub 2012 Apr 11. Clearance of initial mucoid Pseudomonas aeruginosa in patients with cystic fibrosis. Reviewer: Dr. Craig Becker

Oct. 29, 2015

Honey for cough

Article: Arch Pediatr Adolesc Med. 2007 Dec;161(12):1140-6. Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents. Reviewer: Dr. Sevilay Dalabih

Oct. 8, 2015

Pediatric outcomes in rural vs. urban hospitals

Article: Pediatrics. 2004 Oct;114(4):e400-8. Pediatric Outcomes in Rural and Urban Hospitals Reviewer: Dr. Eric Neverman

Oct. 1, 2015

Parental Effect on Adolescent Risk of Cyberbullying

Article: J Youth Adolesc. 2015 May;44(5):1039-47. doi: 10.1007/s10964-014-0242-4. Epub 2014 Dec 13. The protective effects of parental monitoring and internet restriction on adolescents' risk of online harassment. Reviewer: Dr.Gordon Duval

Sept. 24, 2015

Bionic Pancreas for Type 1 Diabetes

Article: N Engl J Med. 2014 Jul 24;371(4):313-25. doi: 10.1056/NEJMoa1314474. Epub 2014 Jun 15. Outpatient glycemic control with a bionic pancreas in type 1 diabetes. Reviewer: Dr. Sajal Patel

Sept. 17, 2015

Barriers to screening adolescents for HIV in the Emergency Department

Article: Pediatr Emerg Care. 2015 Sep;31(9):621-6. doi: 10.1097/PEC.0000000000000370. Practices, Beliefs, and Perceived Barriers to Adolescent Human Immunodeficiency Virus Screening in the Emergency Department. Reviewer: Dr. Lisa Hiskey

Sept. 10, 2015

Does rudeness affect medical performance?

Article: Pediatrics. 2015 Sep;136(3):487-95. doi: 10.1542/peds.2015-1385. Epub 2015 Aug 10. The Impact of Rudeness on Medical Team Performance: A Randomized Trial. Reviewer: Dr. Samantha Hathaway

Sept. 3, 2015

When to repeat blood cultures in pediatric oncology patients with febrile neutropenia?

Article: Pediatr Blood Cancer. 2013 Jun;60(6):923-7. doi: 10.1002/pbc.24358. Epub 2012 Oct 9. Repeating Blood Cultures in Neutropenic Children with Persistent Fevers When the Initial Blood Culture is Negative Reviewer: Dr. David Gubernick

Aug. 27, 2015

Non-Contact Bat Exposure: Is rabies prophylaxis worth the cost?

Article: Bats in the Bedroom, Bats in the Belfry: Reanalysis of the Rationale for Rabies Postexposure Prophylaxis Reviewer: Dr. Blake Barnes

Aug. 20, 2015

Does repeating bilirubin levels prior to discharge lead to decreased readmissions in infants admitted for hyperbilirubinemia?

Article: Hosp Pediatr. 2015 Feb;5(2):74-8. doi: 10.1542/hpeds.2014-0074. The utility of inpatient rebound bilirubin levels in infants readmitted after birth hospitalization for hyperbilirubinemia Reviewer: Dr. Audrey Bush

Aug. 13, 2015

Does Heart Rate Characteristic Monitoring Decrease Mortality from Sepsis in the NICU?

Article:J Pediatr. 2011 December ; 159(6): 900–906.e1. doi:10.1016/j.jpeds.2011.06.044. Mortality reduction by heart rate characteristic monitoring in very low birth weight neonates: a randomized trial Reviewer: Dr. Rebecca Fish

June 25, 2015

Pacifier use and breastfeeding

Article: Cochrane Database Syst Rev. 2012 Jul 11;7:CD007202. doi: 10.1002/14651858.CD007202.pub3. Effect of restricted pacifier use in breastfeeding term infants for increasing duration of breastfeeding. Reviewer: Dr. Kailey Wilson

June 4, 2015

Effects of formula supplementation on breastfeeding duration

Article: Pediatrics. 2013 Jun;131(6):1059-65. doi: 10.1542/peds.2012-2809. Epub 2013 May 13. Effect of early limited formula on duration and exclusivity of breastfeeding in at-risk infants: an RCT. Reviewer: Dr. Audrey Bush

May 28, 2015

Abdominal radiograph use for suspected constipation in children

Article: J Pediatr. 2014 Jan;164(1):83-88.e2. doi: 10.1016/j.jpeds.2013.08.074. Epub 2013 Oct 13. Pediatric Abdominal Radiograph Use, Constipation, and Significant Misdiagnoses Reviewer: Dr. Dana Vietti

May 21, 2015

Does videoconferencing work for treatment of depression in children?

Article: Telemed J E Health. 2003 Spring;9(1):49-55. Treating Childhood Depression over Videoconferencing Reviewer: Dr. Lisa Hiskey

May 7, 2015

IV vs oral antibiotics for postdischarge treatment of osteomyelitis

Article: JAMA Pediatr. 2015 Feb;169(2):120-8. doi: 10.1001/jamapediatrics.2014.2822. Comparative Effectiveness of Intravenous vs Oral Antibiotics for Postdischarge Treatment of Acute Osteomyelitis in Children Reviewer: Dr. Adam Massey

April 30, 2015

Treatment of functional abdominal pain

Article: Pediatrics. 2015 Mar;135(3):522-35. doi: 10.1542/peds.2014-2123. Epub 2015 Feb 9. Nonpharmacologic Treatment of Functional Abdominal Pain Disorders: A Systematic Review Reviewer: Dr. Meghann Houck

April 16, 2015

Anti-Tumor Necrosis Factor Therapy for Pediatric IBD, Risk of Serious Infection and Lymphoma

Article: Clin Gastroenterol Hepatol. 2014 Sep;12(9):1443-51; quiz e88-9. doi: 10.1016/j.cgh.2014.01.021. Epub 2014 Jan 22. Risks of serious infection or lymphoma with anti-tumor necrosis factor therapy for pediatric inflammatory bowel disease: a systematic review. Reviewer: Dr. Lance Robbins

April 9, 2015

Role of Neutrophil CD64 in the Evaluation of Neonatal Sepsis

Article: Am J Perinatol. 2015 Mar;32(4):331-6. doi: 10.1055/s-0034-1384644. Epub 2014 Jul 31. Neutrophil CD64 as a diagnostic marker of sepsis: impact on neonatal care Reviewer: Dr. Eric Neverman

March 26, 2015

Intermittent montelukast in young children with wheeze

Article: Lancet Respir Med. 2014 Oct; 2(10): 796–803. Intermittent montelukast in children aged 10 months to 5 years with wheeze (WAIT trial): a multicentre, randomised, placebo-controlled trial Reviewer: Dr. Rebekah Nevel

March 19, 2015

Immunotherapy for the desensitization of peanut allergy in children

Article: Lancet. 2014 Apr 12; 383(9925): 1297–1304. Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial Reviewer: Dr. Sirish Rao

March 12, 2015

Does resident schedule affect patient safety?

Article: CMAJ. 2015 Mar 17;187(5):321-9. doi: 10.1503/cmaj.140752. Epub 2015 Feb 9. Patient safety, resident well-being and continuity of care with different resident duty schedules in the intensive care unit: a randomized trial. Reviewer: Dr. Meghann Houck

March 5, 2015

Epidemiology of community acquired pneumonia in children

Article: N Engl J Med. 2015 Feb 26;372(9):835-45. doi: 10.1056/NEJMoa1405870. Community-acquired pneumonia requiring hospitalization among U.S. children. Reviewer: Dr. Clark

Feb. 26, 2015

Can Emollients Prevent Eczema in Newborns?

Article: J Allergy Clin Immunol. 2014 Oct;134(4):818-23. doi: 10.1016/j.jaci.2014.08.005. Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention. Reviewer: Dr. Blake Barnes

Feb. 19, 2015

Does hand held cardiac ultrasound help in diagnosis

Article: Eur Heart J Cardiovasc Imaging. 2013 Apr;14(4):323-30. doi: 10.1093/ehjci/jes140. Epub 2012 Jul 24. Pocket-size hand-held cardiac ultrasound as an adjunct to clinical examination in the hands of medical students and junior doctors. Reviewer: Dr. Natalie Behrle

Feb. 9, 2015

Oral feeds and CPAP

Article: Dysphagia. 2014 Nov 8 Safety and Efficacy of Oral Feeding in Infants with BPD on Nasal CPAP. Reviewer: Christopher Brownsworth

Jan. 29, 2015

Live attenuated vs. inactivated influenza vaccine effects on asthma exacerbations

Article: Pediatr Infect Dis J. 2006 Oct;25(10):860-9. Comparison of the efficacy and safety of live attenuated cold-adapted influenza vaccine, trivalent, with trivalent inactivated influenza virus vaccine in children and adolescents with asthma. Reviewer: Dr. Hille Corona

Jan. 15, 2015

Rest after concussions

Article:Pediatrics. 2015 Feb;135(2):213-23. doi: 10.1542/peds.2014-0966. Epub 2015 Jan 5. Benefits of strict rest after acute concussion: a randomized controlled trial. Reviewer: Dr. Samantha Hathaway

Dec. 18, 2014

Preparing Adolescents for Adult Care

Article:Pediatrics. 2014 Jun;133(6):e1639-46. doi: 10.1542/peds.2013-2830. Epub 2014 May 19. Preparing adolescents with chronic disease for transition to adult care: a technology program. Reviewer: Dr. Dana Vietti

Nov. 20, 2014

Smoking Cessation Interventions During Child Health Visits To Decrease Parental Smoking

Article: Pediatrics. 2012 Jan;129(1):141-52. doi: 10.1542/peds.2010-3209. Epub 2011 Dec 26. Parental smoking cessation to protect young children: a systematic review and meta-analysis. Reviewer: Dr. Julie Benard

Nov. 10, 2014

Probiotics to prevent antibiotic associated diarrhea

Article: Cochrane Database Syst Rev. 2011 Nov 9;(11):CD004827. doi: 10.1002/14651858.CD004827.pub3. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Reviewer: Dr. Alexandra James

Oct. 30, 2014

Helmet therapy for positional skull deformation

Article: BMJ. 2014 May 1;348:g2741. doi: 10.1136/bmj.g2741. Helmet therapy in infants with positional skull deformation: randomised controlled trial Reviewer: Dr. Gordon Duval

Oct. 23, 2014

Rapid diagnostic tests for strep

Article: Pediatrics. 2014 Oct;134(4):771-781. Epub 2014 Sep 8. Rapid Diagnostic Tests for Group A Streptococcal Pharyngitis: A Meta-analysis Reviewer: Dr. Chad McCormick

Oct. 16, 2014

NPO status and length of stay in infants with bronchiolitis

Article:Hosp Pediatr. 2013 Oct;3(4):366-70. doi: 10.1542/hpeds.2013-0011. Association of NPO Status and Type of Nutritional Support on Weight and Length of Stay in Infants Hospitalized with Bronchiolitis Reviewer: Dr. Lance Robbins

Oct. 9, 2014

Free long-acting contraception and teenage pregnancy

Article: N Engl J Med. 2014 Oct 2;371(14):1316-23. doi: 10.1056/NEJMoa1400506. Provision of no-cost, long-acting contraception and teenage pregnancy Reviewer: by Dr. Sajal Patel

Oct. 2, 2014

Cranberry Juice for the Prevention Recurrent Urinary Tract Infections

Article:Clin Infect Dis. 2012 Feb 1;54(3):340-6. doi: 10.1093/cid/cir801. Epub 2011 Nov 18. Cranberry juice for the prevention of recurrences of urinary tract infections in children: a randomized placebo-controlled trial. Reviewer: Dr. Christian Gonzalez

Sept. 25, 2014

Hydrocolloid dressings prevent CPAP nasal trauma

Article: World J Emerg Med. 2014;5(3):218-22. doi: 10.5847/wjem.j.1920-8642.2014.03.011. Hydrocolloid dressing in preventing nasal trauma secondary to nasal continuous positive airway pressure in preterm infants. Reviewer: Dr. Jennifer Kovatch

Sept. 18, 2014

High dose dexamethasone for croup

Article: Int J Pediatr Otorhinolaryngol. 2007 Mar;71(3):473-7. Epub 2007 Jan 8. A randomized comparison of dexamethasone 0.15 mg/kg versus 0.6 mg/kg for the treatment of moderate to severe croup. Reviewer: Dr. Lauren Kirkpatrick

Sept. 11, 2014

Lecture effectiveness on learning

Article: Arch Pediatr Adolesc Med. 1998 Feb;152(2):190-2. To teach is to learn twice. Resident teachers learn more Reviewer: Dr. Christopher Brownsworth

Sept. 4, 2014

Transport method and treatment outcomes

Article: Pediatrics. 2009 Jul;124(1):40-8. doi: 10.1542/peds.2008-0515. Pediatric specialized transport teams are associated with improved outcomes. Reviewer: Dr. Chistopher Miller

Aug. 28, 2014

High frequency oscillatory ventilation for severe respiratory failure

Article: JAMA Pediatr. 2014 Mar;168(3):243-9. doi: 10.1001/jamapediatrics.2013.4463. Comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. Reviewer: Dr. Matt Clark

Aug. 14, 2014

Motor stereotypies and disability

Article:Pediatr Neurol. 2008 Apr;38(4):267-72. doi: 10.1016/j.pediatrneurol.2007.12.008. Nonautistic motor stereotypies: clinical features and longitudinal follow-up. Reviewer: Dr. Samantha Hathaway

Aug. 7, 2014

Motivational interviewing for obesity treatment

Article: Pediatr Obes. 2014 Apr 14. doi: 10.1111/j.2047-6310.2014.226.x. Motivational interviewing targeting diet and physical activity improves adherence to paediatric obesity treatment: results from the MI Values randomized controlled trial. Reviewer: Dr Faeza Khan

July 17, 2014

Office counseling for child obesity

Article: Int J Obes (Lond). 2007 Apr;31(4):630-6. Epub 2006 Dec 12. Outcome data from the LEAP (Live, Eat and Play) trial: a randomized controlled trial of a primary care intervention for childhood overweight/mild obesity. Reviewer: Dr. Alex James

June 26, 2014

Acanthosis nigricans in identifying children with dysglycemia

Article: Obesity (Silver Spring). 2013 Mar;21(3):E328-33. doi: 10.1002/oby.20129. The association between acanthosis nigricans and dysglycemia in an ethnically diverse group of eighth grade students. Reviewer: Dr. Rula Khreis

June 19, 2014

E cigarettes vs. standard cigarettes in asthma symptoms

Article:Nicotine Tob Res. 2014 Jun;16(6):655-62. doi: 10.1093/ntr/ntt203. Epub 2013 Dec 11. Secondhand exposure to vapors from electronic cigarettes. Reviewer: Dr. Natalie Behrle

June 12, 2014

Bleach baths for Staphylococcus aureus de-colonization

Article: Infect Control Hosp Epidemiol. 2011 Sep;32(9):872-80. doi: 10.1086/661285. Effectiveness of measures to eradicate Staphylococcus aureus carriage in patients with community-associated skin and soft-tissue infections: a randomized trial. Reviewer: Dr. Faeza Khan

June 5, 2014

Ketotifen vs. olopatadine for allergic conjunctivitis

Article: Adv Ther. 2003 Mar-Apr;20(2):79-91. Ketotifen fumarate and olopatadine hydrochloride in the treatment of allergic conjunctivitis: a real-world comparison of efficacy and ocular comfort. Reviewer: Dr. Hille Corona

May 29, 2014

Rate of weight gain in infancy after failure to thrive and adult metabolic disease

Article: J Clin Endocrinol Metab. 2007 Jan;92(1):98-103. Epub 2006 Oct 10. Association of weight gain in infancy and early childhood with metabolic risk in young adults. Reviewer: Dr. Bonni Heithold

May 22, 2014

Ketogenic diet for epilepsy

Article: Lancet Neurol. 2008 Jun;7(6):500-6. doi: 10.1016/S1474-4422(08)70092-9. Epub 2008 May 2. The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial. Reviewer: Dr. Anjali Anders

May 1, 2014

Bullying and adverse health outcomes

Article: J Youth Adolesc. 2013 May;42(5):675-84. doi: 10.1007/s10964-013-9925-5. Epub 2013 Feb 5. Cyber bullying and physical bullying in adolescent suicide: the role of violent behavior and substance use. Reviewer: Dr. Meghann Houck

April 24, 2014

Early inhaled corticosteroids to decrease hospitalization in asthma patients

Article: Thorax. 1998 Dec;53(12):1025-9. First treatment with inhaled corticosteroids and the prevention of admissions to hospital for asthma. Reviewer: Dr. Chad McCormick

April 10, 2014

Effect of lead exposure on IQ

Article: Environ Int. 2012 Apr;40:88-96. doi: 10.1016/j.envint.2011.10.011. Epub 2012 Jan 13. Childhood blood lead levels and intellectual development after ban of leaded gasoline in Taiwan: a 9-year prospective study. Reviewer: Dr. Natalie Behrle

April 3, 2014

Effective messages in vaccine promotion: do they exist?

Article: Pediatrics. 2014 Apr;133(4):e835-42. doi: 10.1542/peds.2013-2365. Epub 2014 Mar 3. Effective messages in vaccine promotion: a randomized trial. Reviewer: Dr. Audrey Southard

March 20, 2014

Making dying better for pediatric patients

Article: Pediatrics. 2013 Jul;132(1):72-8. doi: 10.1542/peds.2013-0470. Epub 2013 Jun 10. Differences in characteristics of dying children who receive and do not receive palliative care. Reviewer: Dr. Samantha Hathaway

March 13, 2014

Music therapy for premature infants

Article: Pediatrics. 2014 Mar;133(3):462-8. doi: 10.1542/peds.2013-2547. Epub 2014 Feb 17. A pacifier-activated music player with mother's voice improves oral feeding in preterm infants. Reviewer: Dr. Rebekah Nevel

March 6, 2014

Does treatment with nebulized hypertonic saline decrease length of stay in hospitalized infants with bronchiolitis?

Article: Clin Microbiol Infect. 2011 Dec;17(12):1829-33. doi: 10.1111/j.1469-0691.2010.03304.x. Epub 2010 Jul 15. Nebulized hypertonic saline treatment in hospitalized children with moderate to severe viral bronchiolitis Reviewer: Dr. Lauren Kirkpatrick

Feb. 27, 2014

Is acetaminophen use in pregnancy linked to ADHD?

Article: JAMA Pediatr. 2014 Feb 24. doi: 10.1001/jamapediatrics.2013.4914. [Epub ahead of print] Acetaminophen Use During Pregnancy, Behavioral Problems, and Hyperkinetic Disorders Reviewer: Dr. Matthew Clark

Feb. 13, 2014

Do enteral feeds affect outcome or mortality in ulcerative colitis?

Article: Gut. 1986 May;27(5):481-5. Controlled trial of bowel rest in the treatment of severe acute colitis Reviewer: Dr. Matthew Clark

Feb. 6, 2014

Is marijuana use a contraindication for breastfeeding?

Article: Neurotoxicol Teratol. 1990 Mar-Apr;12(2):161-8. Maternal marijuana use during lactation and infant development at one year. Reviewer: Dr. Alex James

Jan. 30, 2014

Breastfeeding education for residents

Article: Pediatrics. 2002 Nov;110(5):e59. Effect of an Educational Intervention About Breastfeeding on the Knowledge, Confidence, and Behaviors of Pediatric Resident Physicians Reviewer: Dr. Ragini Kapoor

Jan. 23, 2014

Physicians’ Empathy and Clinical Outcomes for Diabetic Patients

Article: Acad Med. 2011 Mar;86(3):359-64. doi: 10.1097/ACM.0b013e3182086fe1. Physicians’ Empathy and Clinical Outcomes for Diabetic Patients Reviewer: Dr. Dana Vietti

Jan. 9, 2014

3-hydroxybutyrate monitoring at home for Type 1 diabetes

Article: Diabet Med. 2006 Mar;23(3):278-84. Sick day management using blood 3-hydroxybutyrate (3-OHB) compared with urine ketone monitoring reduces hospital visits in young people with T1DM: a randomized clinical trial Reviewer: Dr. Eric Neverman

Dec. 19, 2013

Metformin for weight loss in adolescents

Article: J Pediatr. 2008 Jun;152(6):817-22. doi: 10.1016/j.jpeds.2008.01.018. Epub 2008 Mar 19. Addition of metformin to a lifestyle modification program in adolescents with insulin resistance. Reviewer: Dr. Vincent Horne

Dec. 12, 2013

Non-pharmacological treatment for migraine

Article: Headache. 2010 Feb;50(2):219-23. doi: 10.1111/j.1526-4610.2009.01534.x. Epub 2009 Oct 5. Effectiveness of nonpharmacologic treatment for migraine in young children. Reviewer: Dr. Megan Barry

Nov. 21, 2013

Herbal galactogogues for increased milk production

Article: J Hum Lact. 2013 May;29(2):154-62. doi: 10.1177/0890334413477243. Epub 2013 Mar 6. Systematic review of the efficacy of herbal galactogogues. Reviewer:Dr. Rebecca Fish

Nov. 11, 2013

Does nasal suctioning decrease the length of stay in hospitalized infants with bronchiolitis?

Article: JAMA Pediatr. 2013 May;167(5):414-21. doi: 10.1001/jamapediatrics.2013.36. Suctioning and length of stay in infants hospitalized with bronchiolitis. Reviewer: Dr. Lauren Kirkpatrick

Oct. 24, 2013

How effective is office counseling in gun violence prevention?

Article: Pediatrics. 2008 Jul;122(1):e15-25. doi: 10.1542/peds.2007-2611. Is office-based counseling about media use, timeouts, and firearm storage effective? Results from a cluster-randomized, controlled trial Reviewer: Dr. Cassidy Leonard-Scott

Oct. 17, 2013

Influenza vaccine for otitis media prevention

Article: Pediatr Infect Dis J. 2013 Jun;32(6):669-74. doi: 10.1097/INF.0b013e3182840fe7. Effectiveness of intranasal live attenuated influenza vaccine against all-cause acute otitis media in children. Reviewer: Dr. Andy Ausmus

Oct. 10, 2013

Metered dose inhalers (MDIs) vs. nebulizers for asthma exacerbation

Article: Arch Pediatr Adolesc Med. 1995 Feb;149(2):201-5. Metered-dose inhalers with spacers vs nebulizers for pediatric asthma. Reviewer: Dr. Blake Barnes

Sept. 26, 2013

Ipratropium for inpatient asthma

Article: J Pediatr. 2001 Jan;138(1):51-58. Ipratropium bromide plus nebulized albuterol for the treatment of hospitalized children with acute asthma Reviewer: Dr. Audrey Southard

Sept. 19, 2013

Parental presence and procedure pain

Article: Br J Nurs. 2013 Apr 25-May 8;22(8):470-5. Parental presence and distraction during painful childhood procedures Reviewer: Dr. Lisa Hiskey

Sept. 12, 2013

Necessity of lumbar puncture for suspected neonatal sepsis

Article:Acta Paediatr. 2011 Feb;100(2):303-4. doi: 10.1111/j.1651-2227.2010.02012.x. Epub 2010 Sep 29. Is lumbar puncture (LP) required in every workup for suspected late-onset sepsis in neonates? Reviewer: Dr. Adam Massey

Sept. 5, 2013

Milk consumption and asthma

Article: J R Soc Promot Health. 2004 Mar;124(2):74-80. The effects of exclusion of dietary egg and milk in the management of asthmatic children: a pilot study. Reviewer: Dr. Julie Stuppy

Aug. 29, 2013

IVIG for Stevens Johnson Syndrome

Article: J Rheumatol. 2000 Oct;27(10):2494-7. Intravenous immunoglobulin therapy for children with Stevens-Johnson syndrome. Reviewer: Dr. Vincent Horne

Aug. 22, 2013

Antibiotics and obesity

Article: Int J Obes (Lond). 2013 Jan;37(1):16-23. doi: 10.1038/ijo.2012.132. Epub 2012 Aug 21. Infant antibiotic exposures and early-life body mass Reviewer: Dr. Dana Vietti

Aug. 15, 2013

Outcomes of venom immunotherapy for insect stings

Article: N Engl J Med. 2004 Aug 12;351(7):668-74. Outcomes of allergy to insect stings in children, with and without venom immunotherapy. Reviewer: Dr. Stefanie Schroeder

Aug. 8, 2013

Cephalexin plus trimethoprim-sulfamethoxazole vs. cephalexin for cellulitis

Article: Clin Infect Dis. 2013 Jun;56(12):1754-62. doi: 10.1093/cid/cit122. Epub 2013 Mar 1. Clinical trial: comparative effectiveness of cephalexin plus trimethoprim-sulfamethoxazole versus cephalexin alone for treatment of uncomplicated cellulitis: a randomized controlled trial. Reviewer:Dr. Clayton Butcher

Aug. 1, 2013

Milk consumption and weight gain in adolescents

Article: Arch Pediatr Adolesc Med. 2005 Jun;159(6):543-50. Milk, dairy fat, dietary calcium, and weight gain: a longitudinal study of adolescents. Reviewer:Dr. Christopher Brownsworth

July 25, 2013

PFT’s for asthma

Article: J Pediatr. 2005 Dec;147(6):797-801. The influence of pulmonary function testing on the management of asthma in children Reviewer: Dr. Ragini Kapoor

June 20, 2013

Lactobacillus for the treatment of colic

Article: J Pediatr. 2013 Feb;162(2):257-62. doi: 10.1016/j.jpeds.2012.08.004. Epub 2012 Sep 14. Lactobacillus reuteri DSM 17938 for the Management of Infantile Colic in Breastfed Infants: A Randomized, Double-Blind, Placebo-Controlled Trial Reviewer: Dr. Vince Horne

May 23, 2013

Longterm outcomes of PE tubes for otitis media

Article: N Engl J Med. 2007 Jan 18;356(3):248-61. Tympanostomy Tubes and Developmental Outcomes at 9 to 11 Years of Age Reviewer: Dr. Samantha Hathaway

May 16, 2013

Do infants with cystic fibrosis preserve normal lung function during early infancy?

Article: Thorax. 2012 Oct;67(10):874-81. Epub 2012 Jun 29. Lung function is abnormal in 3-month-old infants with cystic fibrosis diagnosed by newborn screening Reviewer: Dr. Rebekah Nevel

May 9, 2013

Is high flow nasal cannula effective in infants with bronchiolitis?

Article: Intensive Care Med. 2013 Mar 14. Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study. Reviewer: Dr. Andy Ausmus

May 2, 2013

Does pacifier use affect exclusive breastfeeding?

Article: Pediatrics. 2013 Apr;131(4):e1101-7. doi: 10.1542/peds.2012-2203. Epub 2013 Mar 18. Pacifier restriction and exclusive breastfeeding. Reviewer:Dr. Rebekah Beyers

April 25, 2013

Asthma severity scores for children admitted with acute asthma exacerbation

Article: Ann Allergy Asthma Immunol. 2011 Jul;107(1):22-8. doi: 10.1016/j.anai.2011.03.011. Epub 2011 Apr 22. The RAD score: a simple acute asthma severity score compares favorably to more complex scores. Reviewer: Dr. Maya Moody

April 18, 2013

Do fluid boluses improve outcomes in severely ill children?

Article: N Engl J Med. 2011 Jun 30;364(26):2483-95. doi: 10.1056/NEJMoa1101549. Epub 2011 May 26. Mortality after fluid bolus in African children with severe infection. Reviewer: Dr. Blake Barnes

April 11, 2013

Does a DKA protocol help to prevent morbidity?

Article: Crit Care Med. 2007 Jan;35(1):41-6. Mandatory protocol for treating adult patients with diabetic ketoacidosis decreases intensive care unit and hospital lengths of stay: results of a nonrandomized trial. Reviewer: Dr. Matt Clark

March 21, 2013

Intranasal steroids for obstructive sleep apnea after adenotonsillectomy

Article: Pediatrics. 2006 Jan;117(1):e61-6. Intranasal steroids and oral leukotriene modifier therapy in residual sleep-disordered breathing after tonsillectomy and adenoidectomy in children Reviewer: Dr. Tim Hayes

March 14, 2013

Swaddling infants to improve sleep

Article: World J Pediatr. 2011 May;7(2):155-60. doi: 10.1007/s12519-011-0268-6. Epub 2011 May 15. Swaddling: a traditional care method rediscovered. Reviewer: Dr. Laura Miltenberg

March 7, 2013

Headgear for concussion protection

Article: Br J Sports Med. 2008 Feb;42(2):110-5; discussion 115. Epub 2007 Jul 5. The effect of protective headgear on head injuries and concussions in adolescent football (soccer) players. Reviewer: Dr. Megan Barry

Feb. 28, 2013

Is intranasal antihistamine superior to intranasal corticosteroid in the treatment of allergic rhinitis in children?

Article: Ann Allergy Asthma Immunol. 2010 Aug;105(2):168-73. doi: 10.1016/j.anai.2010.06.008. Double-blind, placebo-controlled study of azelastine and fluticasone in a single nasal spray delivery device Reviewer: Dr. Erin Toth

Feb. 14, 2013

How Successful is Exercise in the Treatment of Adolescent Depression?

Article: Eur J Public Health. 2006 Apr;16(2):179-84. Epub 2005 Aug 26. Effects of physical exercise on depression, neuroendocrine stress hormones and physiological fitness in adolescent females with depressive symptoms. Reviewer: Dr. Cassidy Leonard-Scott

Feb. 7, 2013

Does treatment of influenza infection with Tamiflu in children with asthma decrease the risk of acute asthma exacerbation?

Article:Pediatr Infect Dis J. 2005 Mar;24(3):225-32. Oral oseltamivir improves pulmonary function and reduces exacerbation frequency for influenza-infected children with asthma. Reviewer: Dr. Lauren Kirkpatrick

Jan. 31, 2013

Does computer game and television exposure impact sleep patterns in typically developing children?

Article: Pediatrics. 2007 Nov;120(5):978-85. Impact of singular excessive computer game and television exposure on sleep patterns and memory performance of school-aged children Reviewer: Dr. Erica Wiebe

Jan. 30, 2013

Effect of breastfeeding education on residents

Article: Pediatrics. 2002 Nov;110(5):e59. Effect of an Educational Intervention About Breastfeeding on the Knowledge, Confidence, and Behaviors of Pediatric Resident Physicians Reviewer: Dr. Ragini Kapoor

Jan. 24, 2013

Pre-extubation steroids to reduce post-extubation stridor

Articles:Intensive Care Med. 2009 Jun;35(6):977-86. doi: 10.1007/s00134-009-1473-9. Epub 2009 Apr 8. Corticosteroids to prevent extubation failure: a systematic review and meta-analysis Cochrane Database Syst Rev. 2009 Jul 8;(3):CD001000. doi: 10.1002/14651858.CD001000.pub3. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults Reviewer: Dr. Paul Hansen

Jan. 17, 2013

Does a multidisciplinary approach to asthma care improve asthma control?

Article:Chest. 2006 Feb;129(2):292-9. An interdisciplinary intervention for undertreated pediatric asthma Reviewer: Dr. Delene Musielak

Jan. 10, 2013

TV in bedroom and risk of obesity

Article: Int J Obes (Lond). 2007 Apr;31(4):644-51. Epub 2006 Sep 12. Children with a TV in their bedroom at higher risk for being overweight. Reviewer: Dr. Jasmine El-Khatib

Dec. 13, 2012

Xylitol gum chewing in pregnancy for reduction of dental caries in children

Article: J Dent Res. 2010 Jan;89(1):56-60. doi: 10.1177/0022034509352958. Xylitol Gum and Maternal Transmission of Mutans Streptococci Reviewer: Dr. Josh Brickner

Nov. 29, 2012

Antibiotic prophylaxis for mammalian bites

Article: Cochrane Database Syst Rev. 2001;(2):CD001738. Antibiotic prophylaxis for mammalian bites Reviewer: Dr. Alex James

Nov. 15, 2012

IV steroids for acute spinal cord injury

Article: Pediatr Surg Int. 2012 Mar;28(3):287-94. Epub 2011 Oct 13. A review: the role of high dose methylprednisolone in spinal cord trauma in children Reviewer: Dr. Jason Prostrollo

Nov. 8, 2012

Antibiotic prophylaxis for recurrent UTI

Article: N Engl J Med. 2009 Oct 29;361(18):1748-59. Antibiotic prophylaxis and recurrent urinary tract infection in children Reviewer: Dr. Rebecca Fish

Nov. 1, 2012

Allergen-specific IgE testing vs. oral food challenge for food allergy diagnosis

Article: J Pediatr. 2011 Apr;158(4):578-583.e1. Epub 2010 Oct 28. Oral Food Challenges in Children with a Diagnosis of Food Allergy Reviewer: Dr. Audrey Southard

Oct. 25, 2012

Early feeding and necrotizing enterocolitis in preterm infants

Article: Pediatrics. 2012 May;129(5):e1260-8. Epub 2012 Apr 9. Early or delayed enteral feeding for preterm growth-restricted infants: a randomized trial. Reviewer: Dr. Anjali Anders

Oct. 18, 2012

Tympanometry in the diagnosis of otitis media

Article: Pediatrics. 2004 Jul;114(1):177-81. A randomized clinical trial to assess the effects of tympanometry on the diagnosis and treatment of acute otitis media Reviewer: Dr. Faeza Khan

Oct. 11, 2012

Intuniv (Guanfacine) for ADHD

Article: J Am Acad Child Adolesc Psychiatry. 2012 Jan;51(1):74-85.e2. Epub 2011 Nov 25. A Controlled Trial of Extended-Release Guanfacine and Psychostimulants for Attention-Deficit/Hyperactivity Disorder Reviewer:Dr. Clayton Butcher

Oct. 4, 2012

Exposure to cold temperature and the common cold

Article: Fam Pract. 2005 Dec;22(6):608-13. Epub 2005 Nov 14. Acute cooling of the feet and the onset of common cold symptoms Reviewer: Dr. Matt Arnold

Sept. 27, 2012

Permethrin vs. ivermectin for scabies

Article: Indian J Dermatol Venereol Leprol. 2011 Sep-Oct;77(5):581-6. Topical permethrin and oral ivermectin in the management of scabies: a prospective, randomized, double blind, controlled study. Reviewer: Dr. Hille Corona

Sept. 20, 2012

Treatment for acute gastroenteritis in children

Article: Pediatr Int. 2011 Oct;53(5):677-82. doi: 10.1111/j.1442-200X.2011.03325.x. Probiotic, zinc and lactose-free formula in children with rotavirus diarrhea: are they effective? Reviewer: Dr. Julie Stuppy

Sept. 13, 2012

Does parental involvement increase weight loss in their children?

Article: Pediatrics. 2011 Apr;127(4):619-27. Epub 2011 Mar 28. Parent diet modification, child activity, or both in obese children: an RCT. Reviewer: Dr. Stefanie Schroeder

Sept. 6, 2012

MRSA decolonization

Article:J Antimicrob Chemother. 2011 Oct;66(10):2409-17. Epub 2011 Jun 30. Eradication of carriage with methicillin-resistant Staphylococcus aureus: effectiveness of a national guideline Reviewer: Dr. Dana Vietti

Aug. 30, 2012

Treatment of molluscum contagiosum with potassium hydroxide

Article: Pediatr Dermatol. 2006 May-Jun;23(3):279-81. Double-blind, randomized, placebo-controlled trial of the use of topical 10% potassium hydroxide solution in the treatment of molluscum contagiosum. Reviewer: Dr. Eric Neverman

Aug. 23, 2012

Long-term outcomes of congenital heart defects

Article: J Pediatr. 2008 Jul;153(1):55-60. Epub 2008 Feb 11. Developmental and functional outcomes at school entry in children with congenital heart defects. Reviewer: Dr. Liz Remus

Aug. 16, 2012

Nebulized hypertonic saline for wheezing

Article: Pediatrics. 2012 Jun;129(6):e1397-403. Epub 2012 May 21. Hypertonic saline and acute wheezing in preschool children Reviewer: Dr. Bonni Heithold

Aug. 2, 2012

Symptoms of primary tooth eruption

Article:Pediatrics. 2011 Sep;128(3):471-6. Epub 2011 Aug 8. Prospective longitudinal study of signs and symptoms associated with primary tooth eruption. Reviewer: Dr. Laura Miltenberg

June 28, 2012

Effect of sodium concentration in IV fluids in DKA

Article: J Clin Res Pediatr Endocrinol. 2011;3(3):149-53. doi: 10.4274/jcrpe.v3i3.29. Efficiency of fluid treatments with different sodium concentration in children with type 1 diabetic ketoacidosis Reviewer: Dr. Andy Ausmus

June 21, 2012

Diagrams to reduce parent acetaminophen dosing errors

Article: Acad Pediatr. 2011 Jan-Feb;11(1):50-7 Use of a pictographic diagram to decrease parent dosing errors with infant acetaminophen: a health literacy perspective Reviewer: Dr. Maya Moody

June 14, 2012

Effect of spanking on aggressive behavior

Article: Pediatrics. 2010 May;125(5):e1057-65. Epub 2010 Apr 12. Mothers' spanking of 3-year-old children and subsequent risk of children's aggressive behavior. Reviewer: Dr. Smruthi Sanath

June 7, 2012

Continuous vs. intermittent albuterol for status asthmaticus

Article: Crit Care Med. 1993 Oct;21(10):1479-86. A prospective, randomized study of continuous versus intermittent nebulized albuterol for severe status asthmaticus in children Reviewer: Dr. Heidi Erickson

May 31, 2012

Transpyloric tube feeding and aspiration pneumonia risk

Article: J Perinatol. 2009 May;29(5):372-5. Epub 2009 Feb 26. Transpyloric tube feeding in very low birthweight infants with suspected gastroesophageal reflux: impact on apnea and bradycardia. Reviewer: Dr. Matt Clark

May 10, 2012

Ultrasound screening for neonate ear tags

Article: J Pediatr. 2002 Sep;141(3):388-91. Pre-auricular tags and pits in the newborn: the role of renal ultrasonography Reviewer: Dr. Nabila Khaleel

May 3, 2012

Terbinafine vs. griseofulvin in treatment of tinea capitis

Article: Int J Dermatol. 2012 Apr;51(4):455-8. doi: 10.1111/j.1365-4632.2011.05341.x. Comparative evaluation of griseofulvin, terbinafine and fluconazole in the treatment of tinea capitis. Reviewer Dr. Erin Toth

April 26, 2012

Honey for acute cough

Article: Cochrane Database Syst Rev. 2012 Mar 14;3:CD007094. Honey for acute cough in children Reviewer: Dr. Christopher Brownsworth

April 19, 2012

Steroids for Kawasaki Disease vasculitis

Article:Eur J Pediatr. 2012 Mar;171(3):571-8. Epub 2011 Nov 5. A meta-analysis on the effect of corticosteroid therapy in Kawasaki disease. Reviewer: Dr. Bonni Heithold

April 15, 2012

Fluticasone propionate vs. budesonide for asthma symptoms

Article: J Pediatr. 1999 Apr;134(4):422-7. Efficacy and safety of high-dose inhaled steroids in children with asthma: a comparison of fluticasone propionate with budesonide Reviewer: Dr. Kevin Tompkins

April 12, 2012

Food allergy and timing of solids

Article: Am J Clin Nutr. 2011 Dec;94(6 Suppl):2012S-2017S. Epub 2011 May 4. Early diet and the risk of allergy: what can we learn from the prospective birth cohort studies GINIplus and LISAplus? Reviewer: Dr. Jasmine El-Khatib

March 29, 2012

Efficacy of lipid-lowering medications for children with dyslipidemia

Article:J Pediatr. 2003 Jul;143(1):74-80. Efficacy and safety of atorvastatin in children and adolescents with familial hypercholesterolemia or severe hyperlipidemia: a multicenter, randomized, placebo-controlled trial. Reviewer: Dr. Liz Remus

March 8, 2012

CPAP vs. surfactant for preterm infants

Article: N Engl J Med. 2010 May 27;362(21):1970-9. Epub 2010 May 16 Early CPAP versus Surfactant in Extremely Preterm Infants Reviewer: Dr. Delene Musielak

March 1, 2012

Ondansetron for gastroenteritis

Article: N Engl J Med. 2006 Apr 20;354(16):1698-705. Oral ondansetron for gastroenteritis in a pediatric emergency department. Reviewer: Dr. Vincent Horne

Feb. 23, 2012

Oseltamivir for influenza post-exposure prophylaxis

Article: J Infect Dis. 2004 Feb 1;189(3):440-9. Epub 2004 Jan 26. Management of influenza in households: a prospective, randomized comparison of oseltamivir treatment with or without postexposure prophylaxis. Reviewer: Dr. Lance Goodall

Feb. 16, 2012

Lansoprazole for asthma

Article: JAMA. 2012 Jan 25;307(4):373-81. Lansoprazole for children with poorly controlled asthma: a randomized controlled trial. Reviewer: Dr. Paul Hansen

Feb. 9, 2012

Neonatal release of ankyloglossia

Article: Pediatrics. 2011 Aug;128(2):280-8. Epub 2011 Jul 18. Efficacy of neonatal release of ankyloglossia: a randomized trial. Reviewer: Dr. Rebekah Nevel

Feb. 1, 2012

Circumcision and the prevention of HIV

Article: Lancet. 2007 Feb 24;369(9562):643-56. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial Reviewer: Dr. Ragini Kapoor

Feb. 1, 2012

Antipyretic use and preventing recurrence of febrile seizures

Article: Arch Pediatr Adolesc Med. 2009 Sep;163(9):799-804. Antipyretic agents for preventing recurrences of febrile seizures: randomized controlled trial. Reviewer: Dr. Anjali Anders

Jan. 19, 2012

Specimen collection methods for chlamydia and gonorrhea screening

Article: J Pediatr Adolesc Gynecol. 2008 Dec;21(6):355-60. Evaluation of self-collected vaginal swab, first void urine, and endocervical swab specimens for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in adolescent females." Reviewer: Dr. Danielle Leivian

Jan. 12, 2012

Doubling the dose of inhaled corticosteroids for acute asthma exacerbation

Article: Arch Dis Child. 1998 Jul;79(1):12-7 Treatment of acute asthmatic exacerbations with an increased dose of inhaled steroid. Reviewer: Dr. Lauren Kirkpatrick

Jan. 5, 2012

Expedited Partner Treatment vs. Standard Partner Referral

Article: Sex Transm Dis. 2010 Oct;37(10):602-7. Expedited partner therapy: a robust intervention. Reviewer: Dr. Meghann Houck

Dec. 21, 2011

Melatonin for insomnia in children

Article: J Am Acad Child Adolesc Psychiatry. 2003 Nov;42(11):1286-93. Melatonin improves health status and sleep in children with idiopathic chronic sleep-onset insomnia: a randomized placebo-controlled trial." Reviewer: Dr. Erica Wiebe

Dec. 2, 2011

Oral steroid dosage for outpatient asthma exacerbation

Article:Chest. 2002 Aug;122(2):624-8. Adverse behavioral effects of treatment for acute exacerbation of asthma in children: a comparison of two doses of oral steroids Reviewer: Dr. Brett Moore

Dec. 1, 2011

Procalcitonin for diagnosing severe bacterial infections

Article: Pediatr Infect Dis J. 2007 Aug;26(8):672-7. Procalcitonin and C-reactive protein as diagnostic markers of severe bacterial infections in febrile infants and children in the emergency department Reviewer: Dr. Tim Hayes

Dec. 1, 2011

Acetaminophen, ibuprofen, or both for fever in children?

Article: Arch Pediatr Adolesc Med. 2006 Feb;160(2):197-202. Antipyretic treatment in young children with fever: acetaminophen, ibuprofen, or both alternating in a randomized, double-blind study Reviewer: Dr. Julie Stuppy

Dec. 1, 2011

Rice cereal thickening to treat GERD in infants

Article: Pediatrics. 2008 Dec;122(6):e1268-77. Epub 2008 Nov 10. The effect of thickened-feed interventions on gastroesophageal reflux in infants: systematic review and meta-analysis of randomized, controlled trials Reviewer: Dr. Erin Toth

Oct. 20, 2011

Heart murmur – innocent or not?

Article:Arch Pediatr Adolesc Med. 1996 Feb;150(2):169-74. Cardinal clinical signs in the differentiation of heart murmurs in children Reviewer: Dr. Clayton Butcher

Oct. 13, 2011

Dose response of influenza vaccine

Article: Pediatrics. 2011 Aug;128(2):e276-89. Epub 2011 Jul 18. Randomized controlled trial of dose response to influenza vaccine in children aged 6 to 23 months. Reviewer: Dr. Anjali Anders

Sept. 29, 2011

Action plans for children with asthma

Article: Arch Pediatr Adolesc Med. 2008 Feb;162(2):157-63. Systematic review of randomized controlled trials examining written action plans in children: what is the plan? Reviewer: Dr. Ragini Kapoor

Sept. 22, 2011

Lumbar puncture for complex febrile seizure

Article: Pediatrics. 2010 Jul;126(1):62-9. Epub 2010 Jun 21 Yield of lumbar puncture among children who present with their first complex febrile seizure. Reviewer: Dr. Sarah Smitherman

Sept. 6, 2011

Axillary versus rectal temperature

Article:BMJ. 2000 Apr 29;320(7243):1174-8. Temperature measured at the axilla compared with rectum in children and young people: systematic review. Reviewer: Dr. Vincent Horne

Aug. 29, 2011

Parenteral fish oil for cholestasis in infants

Article: Ann Surg. 2009 Sep;250(3):395-402. Parenteral fish oil improves outcomes in patients with parenteral nutrition-associated liver injury Reviewer: Dr. Bonni Heithold

Aug. 25, 2011

Whey hydrosolate for infant colic

Article: Pediatrics. 2000 Dec;106(6):1349-54. Infantile colic: crying time reduction with a whey hydrolysate: A double-blind, randomized, placebo-controlled trial. Reviewer: Dr. Robert Mildenhall

Aug. 18, 2011

Weight loss for improvement of pseudotumor cerebri papilledema

Article: Ophthalmology. 1998 Dec;105(12):2313-7. The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri) Reviewer: Dr. Cassidy Leonard-Scott

Aug. 11, 2011

Topical or oral antibiotics for otitis media with PE tubes

Article: Pediatrics. 2006 Sep;118(3):e561-9. Epub 2006 Jul 31. Topical ciprofloxacin/dexamethasone superior to oral amoxicillin/clavulanic acid in acute otitis media with otorrhea through tympanostomy tubes. Reviewer: Dr. Rebekah Beyers

July 12, 2011

Atypical antipsychotics for anorexia nervosa

Article Title: Olanzapine in the treatment of low body weight and obsessive thinking in women with anorexia nervosa: a randomized, double-blind, placebo-controlled trial Reviewer: Dr. Tim Hayes

July 12, 2011

VapoRub for onychomycosis

Article Title: In vitro antagonistic activity of monoterpenes and their mixtures against 'toe nail fungus' pathogens. Reviewer: Dr. Alfred Johnson

May 3, 2011

Gluten free diet and autism

Article: The gluten-free, casein-free diet in autism: results of a preliminary double blind clinical trial. Reviewer: Dr. Erica Wiebe

May 3, 2011

Baseline neuropsychological testing for concussion management

Article: Test-retest reliability of computerized concussion assessment programs Reviewer: Dr. Kevin Tompkins

April 20, 2011

VapoRub for cough

Article:Vapor rub, petrolatum, and no treatment for children with nocturnal cough and cold symptoms. Reviewer: Dr. Laura Miltenberg

April 10, 2011

Risk in febrile infants with UTI

Article: Febrile infants with urinary tract infections at very low risk for adverse events and bacteremia. Reviewer: Dr. Laura Hesemann

March 31, 2011

Melatonin for insomnia

Article: J Child Neurol. 2001 Feb;16(2):86-92. Melatonin for chronic sleep onset insomnia in children: a randomized placebo-controlled trial. Reviewer: Nabila Khaleel

March 21, 2011

Clonidine for ADHD

Article: Clonidine for attention-deficit/hyperactivity disorder: I. Efficacy and tolerability outcomes. Reviewer: Dr. Liz Remus

March 11, 2011

Hepatic transaminase and child abuse recognition

Article: Utility of hepatic transaminases to recognize abuse in children Reviewer: Dr. Paul Hansen

March 4, 2011

Vitamin D supplementation and breastfeeding

Article: Vitamin D deficiency in breastfed infants in Iowa Reviewer: Dr. Jason Hagely

Feb. 18, 2011

Vitamin D and asthma

Article: Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study Reviewer: Dr. Brooke Colbert

Feb. 17, 2011

Insulin therapy for newly-diagnosed diabetics

Article: A randomized, controlled trial comparing twice-a-day insulin glargine mixed with rapid-acting insulin analogs versus standard neutral protamine Hagedorn (NPH) therapy in newly diagnosed type 1 diabetes. Reviewer: Dr. Heidi Erickson

Jan. 28, 2011

Azithromycin and acute asthma exacerbations

[slideshare id=6893890&doc=azithromycinandasthma-110211104146-phpapp02] Article: The effect of telithromycin in acute exacerbations of asthma Reviewer: Dr. Sarah Smitherman

Jan. 20, 2011

Flouride varnish efficacy

[slideshare id=6893246&doc=fluoridevarnish-110211094739-phpapp01] Article: Fluoride varnish efficacy in preventing early childhood caries Reviewer: Dr. Smruthi Sanath

Jan. 19, 2011

When to get CT for head trauma

Article: Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study Reviewer: Dr. Maya Moody

Dec. 19, 2010

Hypertonic nasal saline for rhinitis

Article: Nasal rinsing with hypertonic solution: an adjunctive treatment for pediatric seasonal allergic rhinoconjunctivitis Reviewer: Dr. Menka Desai

Dec. 15, 2010

Treatment of acute prolonged seizure at home

Article: Intranasal midazolam vs rectal diazepam for the home treatment of acute seizures in pediatric patients with epilepsy Reviewer:Dr. Clayton Butcher

Dec. 2, 2010

Antibiotics for urinary tract infection

Article: Febrile urinary tract infection in children: ampicillin and trimethoprim insufficient as empirical mono-therapy Reviewer: Dr. Em Otte

Nov. 12, 2010

Home spirometry and asthma

Article: Home spirometry and asthma severity in children Reviewer: Dr. Brett Moore

Nov. 4, 2010

GERD in pregnancy and infant scalp hair

Article: Pregnancy folklore revisited: the case of heartburn and hair Reviewer: Dr. Wes Meyer

Oct. 29, 2010

Septic arthritis vs. transient synovitis

[slideshare id=5667150&doc=septicarthritis-101104090832-phpapp01] Article: Validation of a clinical prediction rule for the differentiation between septic arthritis and transient synovitis of the hip in children PICO question: Patient Population: Children with acute hip pain. Intervention: Clinical feature(s) and or diagnostic test(s) that can confirm the diagnosis of SA vs TS. Comparison: The gold standard of joint aspiration.…

Oct. 21, 2010

Chest physical therapy on children hospitalized with acute pneumonia

Article: Chest physical therapy for children hospitalised with acute pneumonia: a randomised controlled trial Reviewer: Dr. Matthew Arnold

Oct. 15, 2010

Stool PCR for H. pylori detection

PICO question: P: Children with chronic upper GI problems I: H pylori Stool-PCR C: Upper Endoscopy O: Diagnosis of H pylori infection Article: Application of Stool-PCR test for diagnosis of Helicobacter pylori infection in children Reviewer: Dr. J.T. Hagen

Oct. 7, 2010

Probiotics for infantile colic

Article:Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized study Reviewer: Dr. Danielle Leivian

Sept. 30, 2010

Outcomes of children exposed to chemotherapy in utero

Article: Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero. Reviewer: Dr. Delene Musielak

Sept. 24, 2010

Use of Singulair in asthma

[slideshare id=5280150&doc=ebm-sum-100924161512-phpapp01] PICO question: How does the addition of a leukotriene receptor antagonist to low-dose inhaled corticosteroids change the asthma control in children with poorly-controlled asthma, as compared to medium-dose inhaled corticosteroids? Article: Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. Bottom line: This randomized, double-blinded, adequately-powered study showed that kids with poorly-controlled…

Sept. 22, 2010

Taste test of oral rehydration solutions

Article: Assessing the palatability of oral rehydration solutions in school-aged children: a randomized crossover trial. Reviewer: Dr. Robert Mildenhall

Aug. 30, 2010

Melatonin for headache in children

[slideshare id=5279805&doc=ebm-headaches-100924152820-phpapp01] PICO question: Does Melatonin have a role in treating chronic headaches in the pediatric population? P: Pediatric population with chronic headaches (migraine or otherwise) I: Melatonin C: Continued care with routine headache therapy O: Improvement in baseline intensity, frequency or duration of headaches Article: Melatonin to prevent migraine or tension-type headache in children…

Aug. 10, 2010

Example: Nebulized hypertonic saline for bronchiolitis

PICO Question: In infants with bronchiolitis, does nebulized hypertonic saline reduce length of hospital stay compared to supportive care? Article: A randomized trial of nebulized 3% hypertonic saline with epinephrine in the treatment of acute bronchiolitis in the emergency department Bottom line: Although his randomized controlled trial adds to the evidence base, the evidence is…