{"id":45,"date":"2010-09-24T14:54:11","date_gmt":"2010-09-24T20:54:11","guid":{"rendered":"http:\/\/muchildhealth.wordpress.com\/?p=45"},"modified":"2010-09-24T14:54:11","modified_gmt":"2010-09-24T20:54:11","slug":"use-of-singulair-for-asthma","status":"publish","type":"post","link":"https:\/\/library.muhealth.org\/muchildhealth\/use-of-singulair-for-asthma\/","title":{"rendered":"Use of Singulair in asthma"},"content":{"rendered":"<p>[slideshare id=5280150&amp;doc=ebm-sum-100924161512-phpapp01]<\/p>\n<p><strong>PICO question<\/strong>: How does the addition of a leukotriene receptor antagonist to low-dose inhaled corticosteroids change the asthma control in children with poorly-controlled asthma, as compared to medium-dose inhaled corticosteroids?<\/p>\n<p><strong>Article:<\/strong> <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20197425\">Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids.<\/a><br \/>\n<strong><br \/>\nBottom line:<\/strong> This randomized, double-blinded, adequately-powered study showed that kids with poorly-controlled asthma were more significantly likely to respond best to a step up in therapy with LABA (long-acting beta agonist).  However, as other patients responded best to step up with ICS (inhaled corticosteroid) or LTRA (leukotriene receptor antagonist), and there have been recent concerns regarding the long-term safety of LABAs, each child should always be managed individually.<br \/>\n<strong><br \/>\nReviewer:<\/strong> Dr. Ada Sum<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[slideshare id=5280150&amp;doc=ebm-sum-100924161512-phpapp01] PICO question: How does the addition of a leukotriene receptor antagonist to low-dose inhaled corticosteroids change the asthma control in children with poorly-controlled asthma, as compared to medium-dose inhaled corticosteroids? Article: Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. Bottom line: This randomized, double-blinded, adequately-powered study showed that kids with poorly-controlled [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[26,4],"tags":[],"class_list":["post-45","post","type-post","status-publish","format-standard","hentry","category-asthma","category-drugs"],"acf":[],"_links":{"self":[{"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/posts\/45","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/comments?post=45"}],"version-history":[{"count":0,"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/posts\/45\/revisions"}],"wp:attachment":[{"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/media?parent=45"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/categories?post=45"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/library.muhealth.org\/muchildhealth\/wp-json\/wp\/v2\/tags?post=45"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}